What DSIP is
DSIP stands for delta sleep-inducing peptide. Its official name is emideltide. It is a nine amino acid peptide first isolated in the 1970s from the brains of rabbits put into deep sleep.
It's sold online for sleep and stress. Decades after its discovery, how it works and whether it reliably improves sleep in people are still unclear.
Regulatory status in 2026
DSIP is not approved, is not on the compounding list, and was rejected for it in 2026.
DSIP is removed from FDA's Category 2 list. Removal does not make it legal to compound.
FDA's advisory committee votes 6 to 7, with one abstention, against adding DSIP to the compounding list. It was the only peptide of seven reviewed that day and the day before to be turned down.
Not approved and not recommended for compounding.
Regulatory status can change. Check the sources linked at the bottom of this page before relying on anything here.
Claims vs. what the research shows
DSIP was studied in people mostly in the 1980s, in small studies with mixed results.
Improves deep sleep.
Small, older human studies show mixed results. Not established.
Insufficient dataHelps with opioid withdrawal.
Proposed in the nomination. Evidence is limited and dated.
Insufficient dataReduces stress.
Not established in human trials.
Insufficient dataStorage and stability
Peptides break down with heat, light, moisture, and repeated freezing and thawing. Degraded product is one common reason two vials of the "same" peptide behave differently. These are general peptide handling practices. Your supplier's certificate of analysis or label takes priority.
Sealed powder (lyophilized)
- Refrigerate at 36 to 46°F (2 to 8°C) for routine storage.
- Freezer is generally used for long-term storage.
- Keep in its original sealed vial, away from light.
- Let a cold vial reach room temperature before opening to limit condensation.
After reconstitution
- Keep refrigerated. Do not freeze.
- Protect from light. Clear glass lets it through.
- Opened multi-dose bacteriostatic water is typically discarded 28 days after first puncture.
- Log the mix date so you know the vial's age at a glance.
Light exposure is easy to overlook in a fridge door that opens dozens of times a day. VIALTIGHT is building stackable cases that block light from every side. See vialtight.com for updates.
Reconstitution math
Concentration is just the amount of peptide divided by the volume of water added. On a U-100 insulin syringe, 100 units equals 1 mL, so each unit is 0.01 mL. Enter what is on your vial label and what you added to see the concentration.
This shows concentration only. It is not a dosing recommendation. VialTracker runs this math for every vial you log and keeps it with the vial's history.
Safety flags
Product quality is unverified. Gray-market vials have been found underdosed, mislabeled, or contaminated. A certificate of analysis from the seller is not the same as independent testing.
Effect is uncertain. Fifty years of research haven't established a clear mechanism or reliable effect.
Human safety is unknown. There is no modern human safety data.
FAQ
Why was DSIP rejected when others passed?
The committee was split, and DSIP narrowly failed. Members weighed limited and dated evidence.
Is DSIP the same as emideltide?
Yes. Emideltide is the official name.
Does VialTracker tell me what to take?
No. VialTracker organizes the information you enter and runs the math. It does not recommend doses, products, or protocols.