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Ipamorelin: status, evidence, storage and handling

What ipamorelin is, how far it got in human testing, where it stands with regulators, and how to store and track a vial.

Reviewed October 11, 2026Not FDA-approvedBanned in sport (WADA S2)4 min read
What it isSynthetic 5 amino acid peptide
FDA statusNot approved for any use
Human evidenceEarly trials, development stopped
StorageCold, dark, minimal freeze-thaw

What Ipamorelin is

Ipamorelin is a synthetic peptide of 5 amino acids that triggers growth hormone release by acting on the ghrelin receptor, the same receptor the body's hunger hormone uses.

Early research described it as more selective than older compounds in its class, with less effect on other hormones such as cortisol. It was later tested in people as a treatment for slowed bowel function after surgery. That program did not lead to an approved drug.

Regulatory status in 2026

Ipamorelin is not an approved drug and is not on the list of substances pharmacies may compound from. It was not part of the 2026 changes.

  1. Ipamorelin is tested in human trials for bowel recovery after surgery. Development does not continue to approval.

  2. FDA's Pharmacy Compounding Advisory Committee votes against adding ipamorelin to the compounding list.

  3. Ipamorelin is not among the peptides removed from Category 2 in April or reviewed in July.

  4. Not approved, not compoundable, and prohibited at all times under WADA class S2 as a growth hormone secretagogue.

Regulatory status can change. Check the sources linked at the bottom of this page before relying on anything here.

Claims vs. what the research shows

Ipamorelin is often sold paired with CJC-1295. Each has its own thin evidence base. The combination has essentially none.

Common claim

Increases growth hormone release.

What the evidence shows

Shown in animal studies and early human pharmacology studies.

Animal or limited evidence
Common claim

Builds muscle, improves sleep, and burns fat.

What the evidence shows

Not shown in controlled human trials.

Insufficient data
Common claim

Has no side effects.

What the evidence shows

Not established. Human safety data is limited to short trials in a narrow setting.

Insufficient data

Storage and stability

Peptides break down with heat, light, moisture, and repeated freezing and thawing. Degraded product is one common reason two vials of the "same" peptide behave differently. These are general peptide handling practices. Your supplier's certificate of analysis or label takes priority.

Sealed powder (lyophilized)

  • Refrigerate at 36 to 46°F (2 to 8°C) for routine storage.
  • Freezer is generally used for long-term storage.
  • Keep in its original sealed vial, away from light.
  • Let a cold vial reach room temperature before opening to limit condensation.

After reconstitution

  • Keep refrigerated. Do not freeze.
  • Protect from light. Clear glass lets it through.
  • Opened multi-dose bacteriostatic water is typically discarded 28 days after first puncture.
  • Log the mix date so you know the vial's age at a glance.

Light exposure is easy to overlook in a fridge door that opens dozens of times a day. VIALTIGHT is building stackable cases that block light from every side. See vialtight.com for updates.

Reconstitution math

Concentration is just the amount of peptide divided by the volume of water added. On a U-100 insulin syringe, 100 units equals 1 mL, so each unit is 0.01 mL. Enter what is on your vial label and what you added to see the concentration.

2.5mg per mL
2,500mcg per mL
25mcg per syringe unit

This shows concentration only. It is not a dosing recommendation. VialTracker runs this math for every vial you log and keeps it with the vial's history.

Safety flags

Product quality is unverified. Gray-market vials have been found underdosed, mislabeled, or contaminated. A certificate of analysis from the seller is not the same as independent testing.

Long-term effects are unknown. No long-term human safety data exists for repeated use outside a hospital setting.

Blends add uncertainty. Pre-mixed CJC-1295 and ipamorelin vials make it harder to know what you have. Each compound should appear separately on the certificate of analysis.

Tested athletes. Prohibited at all times under WADA class S2.

FAQ

Is ipamorelin legal?

It is not FDA-approved and cannot be legally compounded or marketed for human use under current federal rules.

Why is it sold with CJC-1295?

The two act on growth hormone release through different pathways. That pairing comes from marketing and community use, not from completed human trials.

Does VialTracker tell me what to take?

No. VialTracker organizes the information you enter and runs the math. It does not recommend doses, products, or protocols.

Sources

  1. FDA: Pharmacy Compounding Advisory Committee
  2. WADA: Prohibited List

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